Discovery of ‘barometer’ cells that indicate blood pressure in the human kidney
Virginia: Scientists have discovered some cells inside the human kidney that sense blood pressure. We can call them physical barometers.
Experts at the University of Virginia say that these cells act like blood pressure sensors to control pressure. Experts suspected that these cells may be in the kidneys, but this has now been confirmed. Earlier, these sensor-like cells were discovered along the carotid sinus vein in the neck and near the heart. They monitor blood pressure and help normalize the brain by directing it in case of low blood pressure.
Experts have believed since 1957 that a type of renin cell in the kidney works to detect and moderate blood pressure. But they have not been traced for 60 years. Experts from the University of Virginia placed some kidney cells in a laboratory tray and found that they contain baroreceptors that act as a kind of mechanical transducer. They sense pressure outside the cell and send signals to the nucleus inside.
When the pressure on the renin cells was increased, the activity of a gene called renin one also decreased and when the pressure was reduced, that is, when the blood pressure decreased, the activity of renin one increased. It turned out that this is how they keep their blood pressure in moderation.
Dr. Maria Lopez, author of a research paper on this important discovery, says that it is a unique discovery in which baroreceptors have been discovered inside the kidney that feel blood pressure like a cell and keep blood pressure normal.
This research will not only help to understand the fluctuations in blood pressure, but will also reveal new therapies to control this insidious disease.