Discover the genetic cause of heart disease in newborns
New York: A large number of eye-opening children in the world suffer from some kind of congenital heart disease. Now a gene has been discovered that could be a major cause of the disorder.
Phospholipase D1 (PLD1 for short) is an important gene that affects the valve on the right side of the heart and causes a disease in children called neonatal cardiomyopathy.
According to the Journal of Clinical Investigation, 33% of all congenital malformations in children are due to heart defects. The most common of these is valve failure.
Michael Froman, a professor at Stony Brook University’s Rennes School, and his colleagues have been researching and cloning PLD One for the past 25 years. They now know that if there is a defect in this gene, it can affect the heart and valves of children born with it.
PLD-1 acts as an enzyme and emits signals about how cells behave in the form of different hormones. This is how organs are formed. After 25 years of research, the gene has now been linked to heart disease in children.
Research has shown that the PLD-1 gene affects the right heart valve and ventricle. It can be said that this gene can affect the formation and development of the heart.
But these facts have come to light in research on about 2700 newborn heart patients. It was found that in some babies the gene was passed on from the parents and affected the development of the heart in the mother’s womb, in which the seventh week of pregnancy is considered very important.