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Difference between PGS and PGD: What do you need to know?

Olivia by Olivia
February 12, 2022
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PGS stands for Preimplantation Genetic Screening. With the introduction of PGS of embryos, IVF success chances have increased dramatically. A sample of a fertilized embryo should be extracted by a skilled embryologist for providing the genetic characteristics of the embryo. This method is now commonly used in conjunction with fertility treatment. A regenerative specialist may recommend PGS and/or PGD based on a patient’s reproduction background and family health information. The differences between these two forms of embryo examination are explained in this blog. So, if you’d like to know the difference between pgs and pgd, you are at the right post.

PGD:

PGD, also defined as PGT-M, is a type of preimplantation genetic diagnostic screening. If a partner has a confirmed genetic condition in their history that is triggered by a specific mutated gene, PGD can be used to screen every egg to see if it has acquired the gene function and disorder risk. Whenever both the embryo resource and the male donor are transmitters of a similar rare genetic disorder, this egg cell screening can be used to see if their eggs have received all defects.

PGS:

PGS, or Preimplantation Genetic Screening, has become commonly known as PGT-A. This research detects chromosomal defects in embryos. An embryo with forty-six chromosomes is biologically healthy. Any difference from this amount increases the chances of a missed fertilization, loss, or a functional chromosome abnormality such as Mental retardation. Chromosomal problems are rather uncommon, despite their concerning nature. The chromosomal defect is found in over a 1/3 of every embryo from a thirty years old female. Even by the time a woman reaches the age of 40; this proportion has risen to nearly 8o percent abnormal. As a result, in comparison to a young woman, females who try to conceive at an older age may have more fertility problems, a higher risk of miscarriage, and a higher threat of having a kid with a genetic issue like mental retardation. As a consequence, reproductive specialists frequently advise females in their mid-thirties or middle age to undergo PGS.

How are they both different from each other?

PGS PGD
PGS is the test for women of more ages who are expecting a baby. It helps to save them from the pregnancy complications that they may face because of their older age. PGD is the test that uses to determine whether inherited health problems are present in the egg cell or not. This test helps people to get a healthy child.

 

What is the right time to consider these tests?

Egg screening can be beneficial to the couple for a number of reasons. For instance, if a female has a history of pregnancy loss (whether accidentally or as a result of IVF), specialists may find it beneficial to test her eggs for finding any genetic defects. Moreover, there is significant proves that PGS is beneficial for IVF patients older than 35 years. PGD is beneficial for people that have a confirmed gene disorder in their background, as previously mentioned. Ensure to talk to your reproductive professional if you do have some issues or queries regarding embryo screening. They’ll be able to tell you what testing is best for you based on your reproductive history and situation.

What is Egg Screening, and how is it done?

A sample of cells from a human embryo egg is required for both PGD and PGS. The operation is known as egg cell biopsies and is performed frequently in embryology laboratories around the US. Even though the large bulk of eggs survived the examination, there is a slight possibility that an egg will stop growing after this treatment. There isn’t any research that shows that eggs that have been biopsied have a higher risk of pregnancy abnormalities than eggs that have not been biopsied. The cells that are biopsied are sent to a testing lab, whereas the embryonic egg is frozen and kept till the findings are received. The person can next devise a strategy for exploiting the stored eggs. When the patient receives the outcomes, they will consult with the specialist to choose an egg for possible transfer. Many doctors would advise the couples to select an egg that is clear of gene mutations. If PGD was used to screen for a particular gene illness, the patient would almost always opt to implant an egg that is not impacted by the disorder.

Why are these tests necessary?

If you are among the people who have some genetic diseases history in their family background or you are a woman whose age is more than 30 years, you should go through these tests. For professional assistance, you can also contact the International Fertility Group. Below reasons will tell you why these tests are important.

To stay safe from pregnancy problems:

You can keep yourself safe from pregnancy complications if you go through these tests. These tests will save you from future complications, and that’s why we strongly recommend these tests. No one wants complications in this sensitive phase of life, and you should go through these tests as well if you are one of the people we mentioned above.

To have a healthy child:

These tests will help you in having a healthy child, and no historical diseases or age issues can spoil the health or life of your kid. Every parent wants a healthy child and if you are one of them as well, consider PGS or PGD according to the situation.

Conclusion:

There are several people who want to know about PGS and PGD, and if you are one of them as well, this post will help you. You can learn the difference between these two in this article, and there is some more information about these tests as well. If you’d like to know the reasons to go through these tests, you can know the reasons here too. So, read this blog and find out detail about PGS and PGD and the right time to consider tests too.

 

 

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